Medication adherence remains one of the biggest challenges facing health plans, case managers, and pharmacy teams. While members are often labeled as “non-adherent,” many medication adherence barriers stem from social determinants of health (SDOH) that make it difficult to access, afford, understand, or consistently take medications as prescribed. Understanding what may be contributing to adherence gaps can help healthcare organizations identify at-risk members earlier and implement interventions that improve outcomes.
What Are Social Barriers to Medication Adherence?
Social barriers to medication adherence are non-medical factors that prevent individuals from taking medications as prescribed. Common barriers include transportation challenges, financial hardship, housing instability, limited health literacy, language barriers, and food insecurity. These social determinants of health can lead to missed doses, delayed refills, worsening chronic conditions, and higher healthcare utilization.
For health plans, identifying and addressing these barriers is an important component of improving member outcomes, reducing avoidable utilization, and supporting population health initiatives.
1. Transportation Barriers and Medication Access
For many members, getting medications is more challenging than simply visiting a local pharmacy. Transportation limitations, mobility concerns, caregiver dependence, and limited access to pharmacies can all interfere with medication adherence.
Transportation barriers often affect:
- Older adults who no longer drive
- Individuals with disabilities
- Members living in rural communities
- Members with limited caregiver support
- Individuals living in areas with limited pharmacy access
Even when members understand the importance of their medications, refill delays can quickly result in therapy interruptions if transportation challenges are not addressed.
2. Financial Challenges That Lead to Medication Non-Adherence
Financial strain remains one of the most common medication adherence barriers. When members face competing financial priorities, medications may take a back seat to necessities such as food, housing, utilities, or transportation.
Members experiencing financial hardship may:
- Stretch medications by skipping doses
- Delay refills until their next paycheck
- Stop taking medications altogether
- Decline treatment because of cost concerns
Economic instability has been consistently associated with lower medication adherence and poorer health outcomes.
3. Housing Instability and Medication Adherence
Stable housing plays an important role in chronic disease management. Members experiencing housing instability often face significant challenges in maintaining medication routines and continuity of care.
Housing instability can create barriers to:
- Proper medication storage
- Receiving deliveries
- Managing refill schedules
- Maintaining healthcare appointments
- Keeping consistent daily routines
Research has identified housing instability as a social determinant that negatively impacts medication adherence.
4. Health Literacy and Language Barriers
Members cannot follow a treatment plan if they do not fully understand it. While health literacy and language barriers are significant contributors, both can create communication challenges that make medication regimens harder to understand and manage.
Members may struggle to understand:
- Why a medication is prescribed
- How often it should be taken
- Potential side effects
- The importance of staying on therapy
- How medications work together
Language barriers can create additional challenges, particularly for members with limited English proficiency.
5. Food Insecurity and Chronic Disease Management
Food insecurity is often overlooked when discussing medication adherence, yet it has a profound impact on a member’s ability to manage chronic conditions.
Members experiencing food insecurity may:
- Skip medications that require food
- Delay refills to pay for groceries
- Have difficulty following dietary recommendations
- Experience worsening chronic disease control
Food insecurity is one of the social determinants of health most consistently associated with medication adherence challenges.
For members with diabetes, cardiovascular disease, COPD, and other chronic conditions, the combination of poor nutrition and medication non-adherence can significantly increase health risks.
Why Social Barriers Matter for Health Plans
When social barriers to medication adherence go unaddressed, health plans may experience:
- Increased emergency department utilization
- Higher hospitalization rates
- More avoidable care gaps
- Increased total cost of care
- Poorer outcomes among high-risk populations
For health plan case managers and pharmacy teams, identifying social determinants of health early creates opportunities to intervene before medication adherence issues escalate into more serious clinical events. SDOH can significantly influence healthcare outcomes and a person’s ability to manage medications successfully.
How Health Plans Can Identify Members at Risk
Many medication adherence barriers can be identified before members stop taking their medications.
Health plans can proactively identify risk by monitoring:
- Late or missed refills
- Frequent medication gaps
- Reported transportation concerns
- Financial hardship indicators
- Prior SDOH screening results
- Language access needs
- Changes in living situations
Combining pharmacy insights with case management outreach can help uncover underlying social barriers that may not be visible through claims data alone.
Addressing Social Barriers is Essential to Improving Medication Adherence
Improving medication adherence requires more than refill reminders and outreach campaigns. It often requires looking beyond the prescription itself to understand why an adherence gap may exist. Transportation challenges, financial hardship, housing instability, health literacy limitations, language barriers, and food insecurity can all create significant obstacles for members managing chronic conditions.
By identifying social determinants of health that contribute to medication non-adherence and coordinating support across pharmacy and case management teams, health plans can address barriers earlier, improve medication adherence, reduce avoidable utilization, support health equity initiatives, and achieve better member outcomes.
The most effective medication adherence programs move beyond asking, “Why isn’t this member taking their medication?” and instead ask, “What barriers might be standing in their way—and how can we help?”
Where the Right Pharmacy Partner Can Help
Members with complex medication regimens often experience more than one barrier at the same time. A member may have transportation challenges, limited caregiver support, and difficulty understanding a complicated medication schedule, all of which can compound adherence risk.
For case managers, partnering with pharmacy teams that can provide medication coordination, home delivery, adherence packaging, pharmacist support, refill management, and ongoing outreach can help address some of the medication-related burden while the care management team can focus on the member’s broader needs.
If you’d like to learn more or partner with AnewHealth, email info@anewhealthrx.com.


